Saturday, October 11, 2008

glycyrrhetinic acid

glycyrrhetinic acid (the potent sweetener of the licorice root) is an expectorant (a mucous thinner) that inhibits the activity of prostaglandin-metabolizing enzymes (causing lots of prostaglandin activity in the digestive system).

prostaglandins (the bitchinest of all hormones) work in concert with the immune system. their badass reputation comes from regulating classic core body fever. endogenous pyrogenic cytokines (interleukins, interferons, etc.), which are produced in excess in response to an invasive toxin or bacteria, stimulate the hypothalamus to synthesize prostaglandins that modulate the body's core temperature to enable activity of immune mechanisms which fight the pathogen (the reason you take Asprin to break a fever is because it inhibits the production of prostaglandins).

(and) the reason that prostaglandins are the bitchinest of all hormones is because they have such an extensive array of physiological activity through the body.

in the digestive system, the all-star fatty acid derivatives instigate mucous secretion from the stomach lining, both protecting and prolonging the lifespan of the columnar epithelium that so graciously allow for the digestion of food. ergo, tea from boiled licorice root, being concentrated in glycyrrhetinic acid which stimulates prostaglandin secretion in the stomach, is protectice against ulcers, inflammation and general rotting of the digestive tract. incomparably, my favorite medicine.

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